Topic Pages

• Aerobic exercise

  Aerobic exercise, physical activity that increases breathing and heart rate, promotes cardiovascular, brain, and whole-body health.

• Brain-derived neurotrophic factor (BDNF)

  BDNF is a growth factor known for its influence on neuronal health and for its role in mediating the beneficial cognitive effects associated with exercise.

• Cold exposure

  Cold exposure may be a hormetic stressor that reduces inflammation, activates antioxidant enzymes, and boosts the immune system to protect against age-related diseases.

• Depression

  Depression – a neuropsychiatric disorder affecting 322 million people worldwide – is characterized by negative mood and metabolic, hormonal, and immune disturbances.

• Epigenetic aging clocks

  Epigenetic clocks are predictors of biological age based on alterations in an individual's DNA methylation profile.

• Hydrolyzed collagen

  Hydrolyzed collagen, a mixture of peptides derived from collagen, may improve skin aging, decrease arthritis-induced pain, increase bone mineral density, and reduce hypertension.

• Sauna

  Sauna use exposes the body to extreme heat and, in turn, induces protective responses that improve health and may increase healthspan.

• Time-restricted eating

  Time-restricted eating is a form of daily fasting wherein a person eats only during a limited time window, typically 8- to 12-hours.

• Vitamin C

  Vitamin C is an essential nutrient, widely recognized for its antioxidant properties and its roles in many critical processes and pathways.

• Zinc

  Zinc is an essential nutrient that influences growth and development and plays critical roles in immune function, protein synthesis, wound healing, DNA synthesis, and cell division.