Should You Supplement With Lion's Mane? - Rhonda Patrick
The BDNF Protocol Guide
An essential checklist for cognitive longevity — filled with specific exercise, heat stress, and omega-3 protocols for boosting BDNF. Enter your email, and we'll deliver it straight to your inbox.
In this video, Rhonda Patrick discusses:
- If lion's mane benefits brain health
- The possible neuroprotective effects of lion's mane
- The quality concerns with lion's mane supplements
- The clinical studies looking at the effects of lion's mane on cognition
- How lion's mane affects anxiety & depression
- How lion's mane affects gut & metabolic health
- The possible immune system benefits of lion's mane
- The supplement Rhonda thinks benefits the brain more than lion's mane
This clip is a segment from one of our live Members-only AMAs with Rhonda, hosted every month. Join in on the next one and ask Rhonda anything by signing up here
Wanna up your omega-3 game? Download our free fish oil supplementation guide
Hear new content from Rhonda on The Aliquot, our member's only podcast

Listen in on our regularly curated interview segments called "Aliquots" released every week on our premium podcast The Aliquot. Aliquots come in two flavors: features and mashups.
- Hours of deep dive on topics like fasting, sauna, child development surfaced from our enormous collection of members-only Q&A episodes.
- Important conversational highlights from our interviews with extra commentary and value. Short but salient.
Supplements News
- A comprehensive review on the impact of polyphenol supplementation and exercise on depression and brain function parameters.
- Short-term creatine monohydrate use, even without exercise, may boost lean body mass, particularly in women.
- Combining collagen with resistance training enhances tendon strength, improving knee stability in middle-aged men.
- Melatonin supplementation may heighten DNA repair in night shift workers during daytime sleep, potentially reducing cancer risk.
- Supplemental urolithin A enhances cardiac function by preserving mitochondrial function and reducing pro-inflammatory lipids.