Q&A #40 with Dr. Rhonda Patrick (10/01/2022)

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In this Q&A and accompanying show notes, we explore the potential longevity benefits and tradeoffs of rapamycin, the effects of polyphenols on cognition, the variability of urolithin A production in the gut, and more.
We also discuss:
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Coffee alternatives for people who can't tolerate caffeine
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How to increase and maintain bone density with age
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The benefits of Apigenin for sleep
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Whether fat can improve the bioavailability of quercetin and luteolin
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The best way to take a curcumin supplement
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Supplements to prioritize on a budget
Is rapamycin an effective and safe way to increase longevity?
"I would be stunned if rapamycin had similar lifespan-extending effects in humans like it does in lab mice in sterile environments."- Dr. Rhonda Patrick Click To Tweet
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Beginning of Q&A
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Q: Are there any coffee alternatives for people who can't tolerate caffeine?
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Genetic report 1
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Polyphenol topic page 1
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Q: Does Apigenin have any benefits for sleep? 1
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Q: Can the microbiome convert pomegranate to Urolithin A? 1
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Q: What is the best way to take a curcumin supplement?
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Q: What is the GRAIL "liquid biopsy" test?
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Q: Supplements to prioritize on a budget
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Watch previously recorded Q&As with Dr. Rhonda Patrick

Q&A #70 with Dr. Rhonda Patrick (5/3/25)
Dr. Rhonda Patrick discusses cancer prevention, linoleic acid, shingles vaccine and dementia, creatine's kidney effects, and shares her overnight oats recipe.

Q&A #69 with Dr. Rhonda Patrick (4/5/25)
Dr. Rhonda Patrick covers lithium microdosing, reducing homocysteine, aluminum's link to cancer, and beta-alanine and alpha-lipoic acid supplements.

Q&A #68 with Dr. Rhonda Patrick (3/1/25)
Dr. Rhonda Patrick discusses saturated fats and LDL, luteolin's benefits, glyphosate risks, natural vs. artificial flavors, and black cumin seed effects.

Q&A #67 with Dr. Rhonda Patrick (2/8/25)
Dr. Rhonda Patrick discusses microdosing nicotine, GlyNac benefits, intermittent fasting and hair loss, and cold & flu relief.

Q&A #66 with Dr. Rhonda Patrick (1/4/25)
Dr. Rhonda Patrick discusses GLP-1 agonists, alpha-lipoic acid, ubiquinone vs. ubiquinol, calcium needs, and liquid biopsy cancer screening.